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This behavioral assay transpired in subsequent two trials: nonsocial and social odor detection. In the nonsocial odor detection trial, a cotton swab was briefly dipped in a 10% condensed milk Resolution and hung from a corner of the home cage of the topic mouse for 2 min. During this time, the mouse was no cost to take a look at and interact with the contents of its cage with out interference. The amount of time spent within 5 cm of your scented swab or instantly interacting Using the scented cotton swab was recorded.

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= 5 for each genotype). These conclusions suggest which the alterations in SERT purpose in KI mice were being likely a results of lowered catalytic exercise, in which the transportation of each and every 5-HT molecule (

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Mice were put on an elevated round monitor equipment ∼65 cm in diameter. Two open zones and two shut zones, of equivalent duration and all evenly spaced, were contained to the circular monitor. A person mouse was positioned in the middle of an open zone and permitted to examine the maze for 5 min.

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